Clinical Trials
Clinical trials advance medical knowledge and expand treatment options by evaluating the safety and effectiveness of emerging therapies. At Houston Mind & Brain, research efforts are led by a physician with extensive experience in neuroscience and NIH-funded clinical research, bringing academic rigor into a clinical setting.
Join a Research Study!
Access to emerging treatments grounded in clinical research.
Compensation for your time.
Greater understanding of your condition and treatment options.
Opportunity to contribute to advances in psychiatric care.
For more information on our specific studies, please fill out this form:

Join us for a day in the life of a research subject at Houston Mind and Brain! Watch for a view of common procedures - informed consent, questionnaires, vitals, and more.

Hear directly from our owner and Medical Director, Dr. Raymond Cho M.D., M.Sc. as he answers common questions regarding research activities at Houston Mind and Brain.

We are currently enrolling for the following studies:
CANDID - For patients with Major Depressive Disorder
The CANDID study is a fully virtual, observational research study exploring whether patterns in speech and facial expressions can help doctors better understand and measure depression. It does not involve any experimental treatments or changes to your current care.
Here's what participation looks like:
• Up to 5 virtual visits over 6 to 8 weeks (each around 15 to 20 minutes)
• Everything is done online from your computer. No clinic visits, no travel.
• You may receive up to $200 in compensation for your time
A note about Patients starting medication:
If a patient is referred to this study and plans to start a new medication, they can do so immediately after completing their first study visit. Here's what to expect before that happens:
- A brief diagnostic interview with our central raters (conducted remotely)
- A short screening survey completed through Userlytics to confirm your eligibility (which can be completed same-day)
- Scheduling and completing your first study visit, which takes about 15-20 minutes (and can be scheduled immediately after screening is complete)
To enroll in this clinical trial, you must be:
- Age 18-64 years old
- Lives in the United States
- Diagnosed with major depressive disorder with current episode beginning 2-24 months ago
- Not currently on any antipsychotic, benzodiazepines, anxiolytics, prescription non benzo sleep aids
Are you pregnant?
You may be eligible for a research study on sleep and anxiety in the perinatal period.
You may qualify if you are:
1 age 18-45 less than 26 weeks pregnant
Online participation:
Complete 3 surveys: Survey 1: third trimester Survey 2: 2 months postpartum Survey 3: 6 months postpartum
Compensation is provided: 3 Earn up to $60 for completing all surveys, $20 per survey
For more details, see the screening form: https://redcap.link/ci7yed3m

KITES - For patients starting Spravato
Texas A&M and the University of Pittsburgh are conducting a study to explore how digital therapy exercises
combined with IV ketamine or esketamine can improve depression treatment for individuals aged 18-80. The
year-long study is fully remote, so you can participate from anywhere.
Here are 4 reasons why we think you should consider this:
Opportunity to make $650-$750 from home.
You will get enhanced clinical monitoring of your symptoms through the study assessments.
You will be contributing to knowledge of how to help people like yourself.
You will have a chance of getting free access to a portable digital treatment that could help you get the
most of your ketamine treatments by extending the duration of your depression relief.
Interested?
Submit Interest Form below or let your Spravato treater know you're interested!

Why Choose Houston Mind?
MD-led, research-informed brain health - advanced treatments, personalized plans, and practical insurance support.

Insurance Help & Clear Pricing

30+ Years MD Led Psychiatry

Accelerated TMS & Fast Track Paths

Clinical Research & Outcomes Tracking

Integrated Treatment Options

Spravato, Ketamine & KAP Programs








