Depression Treatment in Houston

If you've tried medication, therapy, or both — and you're still not feeling like yourself — you're not out of options. We start with a real evaluation, not a guess, and offer coordinated care including medication management, psychotherapy, TMS, Spravato, and ketamine.

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100+ 5 Star Google Reviews

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We Verify Benefits & Send a Written Estimate

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30+ Years of Clinical Leadership

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TMS, Ketamine & Therapy, Coordinated Into One Plan

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Proven Protocols, Tracked Outcomes

Does This Sound Familiar?

"I feel like I was just handed a prescription and sent on my way."

A five-minute appointment isn't enough to understand what's driving your depression. Our evaluations get to the bottom of things first — before we talk treatment.

"I've been on three different medications and nothing's stuck."

Cycling through medications without a clear plan is exhausting. Our psychiatric providers look at the whole picture — including whether medication is even the right next step.

"I've tried everything. I don't know what else to do."

Between TMS, Spravato, ketamine-assisted psychotherapy, and our ongoing research into new approaches, "tried everything" doesn't always mean "out of options."

How We're Different

01

We evaluate before we treat

Every new patient starts with a thorough evaluation — not a five-minute check-in — so your plan is based on what's actually going on.

02

We offer the full range

Medication, therapy, TMS, Spravato, and ketamine-assisted psychotherapy — coordinated into one plan, not limited to one provider's specialty.

03

We're active in depression research

Dr. Raymond Cho brings three decades of NIH-funded neurostimulation research directly into clinical care. Dr. Alan Prossin directs a research program studying the biological links between inflammation and depression. Ask us about current studies.

Treatment options

  • Medication Management

    Individualized prescribing with regular follow-up to see what's working — and adjust, including addressing side effects, when it isn't.  Learn more

  • Psychotherapy

    Evidence-based talk therapy addressing the patterns behind depression — alone for milder cases, or paired with medication for more persistent symptoms. Learn More

  • TMS Therapy

    A non-medication option that uses magnetic pulses to target the areas of the brain involved in depression and mood regulation — especially worth considering if medications haven't worked well. Learn more

  • Ketamine-Assisted Psychotherapy

    For depression that hasn't responded to standard treatment, ketamine-based options can offer relief on a different timeline — often faster, and through a different mechanism in the brain. Learn more

  • Spravato

    An FDA-approved esketamine nasal spray for treatment-resistant depression, used alongside an oral antidepressant with in-office monitoring. Learn more

  • Intranasal Ketamine

    Racemic ketamine delivered as a nasal spray, offered as a medication-focused option without a bundled therapy session built into each visit. Learn more

You don't have to keep guessing

Whether you're just starting to look for help or feel like you've tried everything, there's a next step worth taking.

Frequently Asked Questions

  • Why isn't my antidepressant working?

    There are a lot of possible reasons — the dose, the specific medication, or the type of depression you're dealing with. It may be time for a fresh evaluation to figure out what will.

  • I've already tried multiple medications. What's next?

    Options can include adjusting the medication approach, adding therapy, or moving to TMS, Spravato, or ketamine-assisted psychotherapy.

  • Can I get a second opinion here?

    Yes — many patients come to us for a fresh evaluation after feeling like their current treatment isn't working.

  • How do I know if I qualify for a clinical trial?

    Eligibility depends on the specific study and your treatment history. Reach out and ask — we'll tell you what's currently available.

  • How soon can I be seen?

    New patient evaluations are typically available the same week you call. 

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I have greatly benefited from the services of Houston Mind & Brain. I would encourage anyone seeking neurological or psychiatric treatment to visit them. I have particularly benefited most from their TMS treatment. It has changed my life for the better in so many ways. They have knowledgeable and friendly staff and providers who really do care about your health and because they are a smaller office you really do get that personal connection with the providers and staff. Highly recommend!

Jessie

We Accept Insurance and Make Care Affordable

We accept most major plans for FDA-cleared treatments (including standard TMS and Spravato). We verify benefits, manage prior authorization, and provide a written estimate before treatment so there are no surprises.

  • Do you accept Medicaid?

    No - we accept Medicare but do not accept Medicaid. If you have questions about coverage, call our team and we’ll help.

  • Will my insurance cover TMS?

    Many commercial plans cover standard TMS when medical-necessity criteria are met. Accelerated/fast-track TMS is often self-pay. We verify benefits and submit prior authorization on your behalf.

  • What if I’m out of network?

    This is uncommon because we are credentialed with most plans. If needed, we can provide a superbill for out-of-network reimbursement.

  • How do I get a written estimate?

    Request a free 20-minute expert call. We’ll run a benefits check, explain likely coverage, and send a written estimate of patient responsibility before any treatment.

  • Can I get sliding scale pricing for TMS?

    Yes. We offer sliding scale pricing for eligible patients and can provide a written cost estimate before treatment. To be considered, we’ll ask for proof of income, such as tax documents.


    At this time, sliding scale pricing is not available for Medicare patients or for accelerated TMS protocols.

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Integrated Care That Delivers Results

Research-informed care that integrates medication management, psychotherapy, TMS, and Spravato/ketamine into a coordinated treatment plan. Treatments are thoughtfully sequenced and monitored within a structured clinical model to support safety, consistency, and meaningful outcomes.

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Why Choose Houston Mind & Brain?

MD-led, research-informed brain health - advanced treatments, personalized plans, and practical insurance support.

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Insurance Help & Clear Pricing

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30+ Years MD Led Psychiatry

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Accelerated TMS & Fast Track Paths

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Clinical Research & Outcomes Tracking

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Integrated Treatment Options

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Spravato, Ketamine & KAP Programs

Hear From Our Patients

100+ Five Star Reviews. Real Stories. Real Recovery.

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Request My Appointment

Request My Appointment

Call or text us at (832) 699-7922 or complete the form below.

Contact Us

What Happens After I Submit This Form?

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We’ll reply within one business day.

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We get you scheduled with the right provider for your needs.

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We verify your insurance and send a written cost estimate before you come in.

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